Analytical Data
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基因名
Tfap2a
- Application
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别名
AP-2 transcription factor (Activating enhancer-binding protein 2-alpha) (Activator protein 2) (AP-2) (Ap2tf) (Tcfap2a)
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种属
Mouse
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表达系统
E. coli
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标签
N- His & C- Myc
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P34056
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表达区间
1-437aa
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分子量
55.0 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Transcription factor AP-2 alpha (Tfap2a) is a crucial nuclear protein involved in the regulation of gene expression during embryonic development and cell differentiation. It belongs to the AP-2 family of transcription factors, which play essential roles in various biological processes, including the development of the nervous system, skin, and other tissues. Abnormal expression of Tfap2a has been implicated in several pathological conditions, including cancer, where it may influence tumor progression and metastasis. The study of recombinant Tfap2a proteins is essential for understanding its functional mechanisms and interactions with other molecules. By producing purified Tfap2a proteins through recombinant DNA technology, researchers can investigate its binding affinities to DNA, identify target genes, and explore its role in cellular signaling pathways. Additionally, recombinant Tfap2a can be utilized in biochemical assays and structural studies to elucidate its three-dimensional conformation and identify potential drug-binding sites. Ultimately, insights gained from these studies may contribute to the development of therapeutic strategies targeting Tfap2a-related pathways in disease management, particularly in cancer and developmental disorders. The growing interest in the functional characterization of Tfap2a underscores its significance in molecular biology and therapeutic research.
