Analytical Data
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基因名
MAST4
- Application
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别名
MAST4; MAST4_HUMAN; Microtubule associated serine/threonine protein kinase member 4; Microtubule-associated serine/threonine-protein kinase 4
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种属
Human
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表达系统
E. coli
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标签
N- His & C- Myc
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O15021
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表达区间
1140-1231aa
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分子量
17.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MAST4 (Microtubule-associated serine/threonine kinase 4) is a member of the MAST (Microtubule-associated serine/threonine) kinase family, which plays a crucial role in regulating microtubule dynamics and cellular processes such as mitosis, migration, and intracellular transport. The study of MAST4 is particularly significant due to its potential implications in cancer biology and neurodegenerative diseases, where aberrant microtubule dynamics can contribute to tumor progression and neuronal dysfunction. Recent research has indicated that MAST4 is overexpressed in various cancer types, suggesting a role in tumorigenesis and poor patient prognosis. Additionally, its kinase activity influences cell cycle progression and apoptosis, making it a potential target for therapeutic intervention. Understanding the structural and functional characteristics of MAST4, especially through recombinant protein studies, can provide insights into its mechanisms of action, interactions with microtubules, and regulatory pathways. Such investigations are critical not only for elucidating the biological roles of MAST4 but also for developing targeted strategies for cancer treatment and understanding its function in neuronal health. This background highlights the importance of MAST4 as a significant player in cellular dynamics and disease, paving the way for future studies aimed at harnessing its potential in clinical applications.
