Analytical Data
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Gene name
PLIN1
- Application
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Alternative Names
PLIN1；PERI；PLIN；Perilipin-1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O60240
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Expression Region
411-496aa
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AA Sequence
EPESEFRDIDNPPAEVERREAERRASGAPSAGPEPAPRLAQPRRSLRSAQSPGAPPGPGLEDEVATPAAPRPGFPAVPREKPKRRV
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Molecular Weight
11.2kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PLIN1 (perilipin 1) is a key protein that plays a crucial role in lipid metabolism and storage within adipocytes. As a component of lipid droplets, PLIN1 regulates the accessibility of lipases to triglycerides, thus influencing lipolysis and energy homeostasis. Research has shown that PLIN1 is not only essential for normal adipocyte function but also contributes to metabolic disorders such as obesity and type 2 diabetes. The interest in PLIN1 has grown due to its potential as a therapeutic target for metabolic diseases. Recombinant PLIN1 protein studies facilitate the understanding of its structural properties, functional mechanisms, and interactions with other proteins or lipids. By producing PLIN1 in recombinant systems, researchers can analyze how alterations in PLIN1 expression or function might impact lipid metabolism, further elucidating its role in adipocyte biology and its implications in metabolic disease pathways. Overall, the investigation of recombinant PLIN1 provides valuable insights that can inform the development of novel strategies for treating dysregulated lipid metabolism.
