Analytical Data
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基因名
ASGR2
- Application
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别名
ASGR2;CLEC4H2;AsialoglycoProtein receptor 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P07307
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表达区间
80-311aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSQSEGHRG AQLQAELRSL KEAFSNFSSS TLTEVQAIST HGGSVGDKIT SLGAKLEKQQ QDLKADHDAL LFHLKHFPVD LRFVACQMEL LHSNGSQRTC CPVNWVEHQG SCYWFSHSGK AWAEAEKYCQ LENAHLVVIN SWEEQKFIVQ HTNPFNTWIG LTDSDGSWKW VDGTDYRHNY KNWAVTQPDN WHGHELGGSE DCVEVQPDGR WNDDFCLQVY RWVCEKRRNA TGEVA
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分子量
29 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ASGR2 (asialoglycoprotein receptor 2) is a crucial membrane protein predominantly expressed in the liver, playing a key role in the clearance of asialoglycoproteins from circulation. It is known to interact with various glycoproteins and holds significance in both physiological and pathological processes, including liver function and immune response. Due to its involvement in hepatic metabolism and potential implications in liver diseases and cancer, ASGR2 has emerged as a target for therapeutic interventions. The study of ASGR2 recombinant proteins facilitates a better understanding of its structure-function relationship and paves the way for developing diagnostic tools and targeted therapies. Recombinant ASGR2 can be produced using advanced biotechnological methods, allowing for detailed studies on receptor binding properties and signal transduction pathways. Exploring the functional characteristics of ASGR2 through recombinant protein studies can yield insights into its role in cellular communication, its mechanism as a facilitator of endocytosis, and its potential association with disease states. Furthermore, understanding ASGR2 could contribute to the development of novel strategies for drug delivery, particularly in liver-targeted therapies. As research progresses, the elucidation of ASGR2's structural features and interaction dynamics will enhance our comprehension of liver physiology and pathology, ultimately supporting the development of innovative clinical applications.












