Analytical Data
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基因名
MIER2
- Application
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别名
KIAA1193
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种属
Human
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表达系统
E. coli
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标签
N- His & C- Myc
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8N344
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表达区间
1-545aa
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分子量
65.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MIER2 (Mi-2/−4 complex interacting protein 2) is a protein that has gained attention in recent years due to its potential role in various cellular processes and diseases. Originally identified as a component of the Mi-2/nucleosome remodeling and deacetylase (NuRD) complex, MIER2 is believed to participate in chromatin remodeling and transcriptional regulation. Its involvement in DNA damage response and cell cycle regulation further highlights its importance in maintaining genomic stability. Research has also suggested that MIER2 may be linked to various cancers and neurodegenerative diseases, making it a potential target for therapeutic interventions. Understanding the structure and function of MIER2, particularly through the study of its recombinant proteins, can provide insights into its biological role and interactions with other cellular partners. Advances in biotechnology have enabled the production of MIER2 recombinant proteins, allowing for detailed biochemical and biophysical analyses. These studies are crucial for deciphering the molecular mechanisms underlying MIER2's functions and for exploring its potential as a biomarker or therapeutic target in disease contexts. As research continues to elucidate the roles of MIER2, it may contribute to novel approaches in the treatment of diseases where its dysfunction is implicated.
