Analytical Data
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Gene name
GDF3
- Application
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Alternative Names
GDF3；Growth/differentiation factor 3
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9NR23
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Expression Region
251-364aa
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AA Sequence
AAIPVPKLSC KNLCHRHQLF INFRDLGWHK WIIAPKGFMA NYCHGECPFS LTISLNSSNY AFMQALMHAV DPEIPQAVCI PTKLSPISML YQDNNDNVIL RHYEDMVVDE CGCG
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GDF3, or Growth Differentiation Factor 3, is a member of the transforming growth factor-beta (TGF-β) superfamily, which plays critical roles in various biological processes, including embryonic development, cell differentiation, and tissue homeostasis. Initially identified in the context of embryonic stem cell research, GDF3 has garnered attention for its involvement in several key developmental pathways and its potential implications in regenerative medicine and cancer biology. Studies have demonstrated that GDF3 acts as a negative regulator of the TGF-β signaling pathway, influencing pluripotency and differentiation of stem cells. Its expression patterns are particularly prominent in early embryonic stages, suggesting a significant role in the maintenance and regulation of stem cell characteristics. Recent research has also highlighted GDF3’s potential as a biomarker in various cancers, further emphasizing the need for understanding its molecular mechanisms and interactions. The recombinant GDF3 protein is being increasingly utilized in laboratory studies to elucidate its functional roles, manipulate stem cell properties, and explore its therapeutic potentials. Understanding GDF3’s biological functions can provide valuable insights into developmental biology, cancer treatment strategies, and regenerative therapies, making it a noteworthy target for ongoing scientific inquiry.
