Analytical Data
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Gene name
CIB2
- Application
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Alternative Names
CIB2；KIP2；Calcium and integrin-binding family member 2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O75838
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Expression Region
1-187aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGNKQTIFTE EQLDNYQDCT FFNKKDILKL HSRFYELAPN LVPMDYRKSP IVHVPMSLII QMPELRENPF KERIVAAFSE DGEGNLTFND FVDMFSVLCE SAPRELKANY AFKIYDFNTD NFICKEDLEL TLARLTKSEL DEEEVVLVCD KVIEEADLDG DGKLGFADFE DMIAKAPDFL STFHIRI
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Molecular Weight
24 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CIB2, or Calcium- and integrin-binding protein 2, is a member of the CIB protein family, which is known for its role in calcium ion binding and cell signaling. The investigation of CIB2 has gained momentum due to its involvement in critical cellular processes, including cell adhesion, migration, and differentiation, particularly in the context of various diseases such as cancer and cardiovascular disorders. Recent studies have indicated that CIB2 interacts with integrins and other signaling proteins, suggesting its potential role as a regulatory molecule in these pathways. Moreover, research has shown that CIB2 may influence the phenotypic characteristics of certain cell types, including osteoblasts and vascular smooth muscle cells. The structural biology of CIB2, especially its calcium-binding motifs, provides insights into its functional mechanisms and interactions at the molecular level. Notably, targeted investigations into the recombinant expression of CIB2 have enabled researchers to elucidate its biochemical properties, facilitating the exploration of its function in health and disease. As a result, understanding the role of CIB2 in cellular signaling networks could reveal novel therapeutic targets for treating diseases associated with dysregulated cell behavior. Additionally, the generation of CIB2 recombinant proteins could serve as valuable tools for further functional studies and potential applications in biotechnology and medicine. The ongoing research on CIB2 is poised to contribute significantly to the broader understanding of its biological significance and therapeutic potential.
