Analytical Data
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基因名
CKS1B
- Application
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别名
CKS1B;CKS1;Cyclin-dependent kinases regulatory subunit 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P61024
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表达区间
1-79aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSMSHKQIY YSDKYDDEEF EYRHVMLPKD IAKLVPKTHL MSESEWRNLG VQQSQGWVHY MIHEPEPHIL LFRRPLPKKP KK
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分子量
12 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CKS1B (Cyclin-Kinase Subunit 1B) is an important protein that plays a crucial role in cell cycle regulation and signal transduction. It functions as a regulatory subunit of cyclin-dependent kinases (CDKs), which are essential for the progression of the cell cycle. Aberrant expression or mutations in CKS1B have been implicated in various cancers, making it a potential biomarker for tumor growth and progression. Studies have shown that CKS1B is involved in the phosphorylation of key substrates that drive cell division and proliferation, linking it to oncogenic processes. The recombinant expression of CKS1B has become a focus of research, allowing scientists to study its structure, function, and interaction with other proteins in greater detail. By producing recombinant CKS1B in various expression systems, researchers aim to elucidate its mechanistic role in cancer and explore its potential as a therapeutic target. Investigations into CKS1B also extend to its involvement in other cellular processes, such as apoptosis and DNA repair, reinforcing its significance in maintaining cellular homeostasis. Understanding the precise functions of CKS1B through recombinant technology not only enhances our comprehension of cancer biology but also paves the way for the development of novel diagnostic and therapeutic strategies.












