Analytical Data
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基因名
CCRL2
- Application
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别名
(Chemokine receptor CCR11)(Chemokine receptor X)(Putative MCP-1 chemokine receptor)
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种属
Human
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表达系统
E. coli
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O00421
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表达区间
1-344aa
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分子量
45.6 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CCRL2, or Chemokine C-C motif receptor-like 2, is a receptor that has garnered significant attention in immunology due to its crucial role in various immune responses, particularly in the regulation of inflammatory processes. This protein is predominantly expressed in immune cells, including monocytes and macrophages, and is involved in the migration and activation of these cells in response to inflammatory stimuli. Research on CCRL2 has shown its potential involvement in several pathological conditions, such as chronic inflammation, autoimmune diseases, and cancer. The receptor interacts with a variety of chemokines, influencing immune cell behavior and contributing to the pathogenesis of these diseases. Understanding the structure and function of CCRL2 is essential for developing targeted therapies that could modulate immune responses for therapeutic benefit. The production of recombinant CCRL2 protein allows for detailed biochemical and functional studies, facilitating insights into its role in immune regulation. Through the study of CCRL2, researchers aim to elucidate its mechanisms of action and explore its potential as a biomarker or therapeutic target, which could lead to innovative treatments for immune-related disorders.
