Analytical Data
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基因名
CSNK2A1
- Application
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别名
CSNK2A1；CK2A1;Casein kinase II subunit alpha
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P68400
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表达区间
1-391aa
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氨基酸序列
MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ
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分子量
52.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CSNK2A1, also known as Casein Kinase 2 alpha 1, is a serine/threonine protein kinase that plays a crucial role in various cellular processes, including cell proliferation, differentiation, and apoptosis. Dysregulation of CSNK2A1 has been implicated in several diseases, particularly cancer, making it a significant target for research. The enzyme is known to modulate multiple signaling pathways and interacts with several substrates, contributing to its essential role in cellular homeostasis. Research involving recombinant CSNK2A1 proteins has advanced our understanding of its biochemical properties, substrate specificity, and regulatory mechanisms. Specifically, the study of its enzymatic activity and interaction with inhibitors provides valuable insights into the potential development of targeted therapies. Furthermore, recombinant expression systems have enabled the production of the kinase in sufficient quantities for structural and functional studies, aiding in the elucidation of its role in various pathophysiological states and contributing to the identification of novel therapeutic approaches. Overall, the study of recombinant CSNK2A1 is pivotal for understanding its role in health and disease, and may pave the way for innovative cancer treatments and other therapeutic strategies.
