Analytical Data
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基因名
CYB5R3
- Application
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别名
CYB5R3；DIA1;NADH-cytochrome b5 reductase 3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P00387
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表达区间
27-301aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSHMFQRST PAITLESPDI KYPLRLIDRE IISHDTRRFR FALPSPQHIL GLPVGQHIYL SARIDGNLVV RPYTPISSDD DKGFVDLVIK VYFKDTHPKF PAGGKMSQYL ESMQIGDTIE FRGPSGLLVY QGKGKFAIRP DKKSNPIIRT VKSVGMIAGG TGITPMLQVI RAIMKDPDDH TVCHLLFANQ TEKDILLRPE LEELRNKHSA RFKLWYTLDR APEAWDYGQG FVNEEMIRDH LPPPEEEPLV LMCGPPPMIQ YACLPNLDHV GHPTERCFVF
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分子量
34 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Cyb5R3, or cytochrome b5 reductase 3, is a crucial enzyme that plays a significant role in the electron transport chain and is involved in various biological processes, including lipid metabolism and the detoxification of reactive oxygen species. Research on Cyb5R3 has gained momentum due to its implications in human health, particularly its association with several diseases, including cardiovascular disorders and certain types of cancer. The enzyme functions to maintain proper cellular redox states and supports the activity of cytochrome b5, which is vital for fatty acid desaturation and cholesterol synthesis. Additionally, mutations in the CYB5R3 gene can lead to metabolic disorders, highlighting the need for further exploration of this protein. Recombinant Cyb5R3 protein has become a focal point in scientific investigations, allowing researchers to study its enzymatic properties, interactions with other molecules, and its role in metabolic pathways. By producing the protein in a controlled environment, scientists can better understand its structure-function relationship, paving the way for potential therapeutic applications. This ongoing research aims to elucidate the mechanisms by which Cyb5R3 influences cellular processes and to develop strategies targeting this enzyme for disease intervention and treatment.
