Analytical Data
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基因名
DECR1
- Application
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别名
DECR1；DECR；SDR18C1;2.4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]. mitochondrial
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q16698
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表达区间
35-335aa
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氨基酸序列
MGSSHHHHHHSSGLVPRGSHM NTEALQSKFFSPLQKAMLPPNSFQGKVAFITGGGTGLGKGMTTLLSSLGA QCVIASRKMDVLKATAEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKV AGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFVTLEIGKQLI KAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMR FNVIQPGPIKTKGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFL CSDYASWINGAVIKFDGGEEVLISGEFNDLRKVTKEQWDTIEELIRKTKG S
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分子量
34 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
DECR1, or Decorin-Related Protein 1, is a member of the short-chain dehydrogenase/reductase (SDR) family, playing a crucial role in various biological processes, including lipid metabolism and oxidative stress responses. Its involvement in metabolic regulation has attracted attention in recent years, particularly in the context of metabolic disorders such as obesity, diabetes, and cardiovascular diseases. DECR1 functions as a key enzyme in the peroxisomal β-oxidation of fatty acids, contributing to the maintenance of cellular homeostasis and energy balance. Emerging studies suggest that DECR1 may affect mitochondrial function and reactive oxygen species (ROS) production, linking it to inflammation and cellular aging. Given these critical roles, researchers are increasingly focused on the molecular mechanisms underlying DECR1's biological functions, aiming to explore its potential as a therapeutic target for metabolic diseases. Understanding DECR1's structure, enzymatic activity, and regulatory pathways could provide deeper insights into metabolic health and disease mechanisms, making it a significant protein in both basic and applied biomedical research. The characterization of DECR1 recombinant proteins allows for the exploration of its enzymatic properties and interactions with other cellular components, paving the way for potential interventions in metabolic dysfunction and related disorders.
