Analytical Data
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基因名
Crh
- Application
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别名
(Corticotropin-releasing factor)(CRF)(Corticotropin-releasing hormone)
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种属
Mouse
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表达系统
E. coli
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标签
N- His-KSI
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8CIT0
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表达区间
145-185aa
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分子量
20.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Crh (Corticotropin-releasing hormone) is a key neuropeptide involved in the regulation of the hypothalamic-pituitary-adrenal (HPA) axis and plays a crucial role in the body's response to stress. Research on Crh recombinant proteins has gained significant attention due to their potential applications in understanding stress-related disorders, such as anxiety and depression. The synthesis of Crh as a recombinant protein enables researchers to investigate its structure, function, and interactions with various receptors in a controlled manner. This has led to advancements in the development of pharmacological agents aimed at modulating the HPA axis. Furthermore, the use of recombinant Crh in animal models has provided insights into its role in behavioral responses and the physiological mechanisms underlying stress resilience and vulnerability. As a result, Crh recombinant proteins not only serve as valuable tools for basic research but also hold promise for therapeutic explorations in the treatment of stress-related conditions. The ongoing studies aim to elucidate the precise mechanisms through which Crh functions within the body and contribute to a deeper understanding of its implications in mental health.
