Analytical Data
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Gene name
WASP
- Application
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Alternative Names
WASP；IMD2；Actin nucleation-promoting factor WAS
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P42768
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Expression Region
2-502aa
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AA Sequence
SGGPMGGRPGGRGAPAVQQNIPSTLLQDHENQRLFEMLGRKCLTLATAVVQLYLALPPGAEHWTKEHCGAVCFVKDNPQKSYFIRLYGLQAGRLLWEQELYSQLVYSTPTPFFHTFAGDDCQAGLNFADEDEAQAFRALVQEKIQKRNQRQSGDRRQLPPPPTPANEERRGGLPPLPLHPGGDQGGPPVGPLSLGLATVDIQNPDITSSRYRGLPAPGPSPADKKRSGKKKISKADIGAPSGFKHVSHVGWDPQNGFDVNNLDPDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQGGLEAVRQEMRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSSEGLVGALMHVMQKRSRAIHSSDEGEDQAGDEDEDDEWDD
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Molecular Weight
53.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
WASP (Wiskott-Aldrich syndrome protein) is a crucial member of the WASP family of proteins, which play significant roles in the regulation of the actin cytoskeleton. Mutations in the WASP gene lead to the Wiskott-Aldrich syndrome, a severe immunodeficiency disorder characterized by eczema, thrombocytopenia, and increased susceptibility to infections. Research on WASP recombinant proteins has gained momentum due to their potential applications in understanding cellular mechanisms and developing therapeutic strategies. These recombinant proteins can be utilized to study the specific functions of WASP in actin polymerization, signal transduction, and cellular motility. Additionally, they serve as valuable tools for investigating the dynamics of cellular responses to various stimuli in a controlled environment. The production of WASP recombinant proteins enables researchers to dissect the molecular pathways involved in actin-related disorders and to explore the potential for gene therapy approaches to treat WASP-related diseases. By engineering these proteins, scientists aim to enhance our understanding of immune system functioning, paving the way for innovative treatments for immune deficiencies and other related conditions. Overall, the study of WASP recombinant proteins not only contributes to basic biological knowledge but also holds promise for future medical advancements.
