Analytical Data
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Gene name
PDCD11
- Application
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Alternative Names
(NF-kappa-B-binding protein)(NFBP)(Programmed cell death protein 11)
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Species
Human
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Source
Yeast
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Tag
C- His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q14690
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Expression Region
1200-1420aa
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Molecular Weight
25.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PDCD11, or Programmed Cell Death 11, is a protein that has gained attention in the fields of immunology and cancer research due to its role in regulating apoptotic pathways and immune responses. Initially identified as a factor influenced by tumor necrosis factor (TNF), PDCD11 is implicated in various cellular processes, including transcription regulation and the modulation of apoptosis in response to stress signals. Recent studies have highlighted its potential involvement in tumor progression, as altered expressions of PDCD11 have been observed in various cancers, including breast and lung cancer. The understanding of PDCD11's function is further expanded by its relationships with other key proteins in apoptotic signaling pathways, suggesting a complex interplay that could influence both normal cellular homeostasis and disease states. The recombinant production of PDCD11 allows researchers to study its structural and functional properties in detail, facilitating the elucidation of its mechanisms in cell death regulation and its potential as a therapeutic target. Moreover, the investigation of PDCD11 interactions with other biomolecules could unveil new insights into cancer therapies and immune modulation strategies. Thus, the research surrounding recombinant PDCD11 not only contributes to our understanding of apoptosis but also holds promise for developing innovative approaches to cancer treatment and enhancing immune responses against tumors.
