Analytical Data
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基因名
EIF1AY
- Application
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别名
EIF1AY;Eukaryotic translation initiation factor 1A. Y-chromosomal
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O14602
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表达区间
1-144aa
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氨基酸序列
MGSSHHHHHHSSGLVPRGSHMGSMPKNKGKGGKNRRRGKNENESEKRELV FKEDGQEYAQVIKMLGNGRLEALCFDGVKRLCHIRGKLRKKVWINTSDII LVGLRDYQDNKADVILKYNADEARSLKAYGELPEHAKINETDTFGPGDDD EIQFDDIGDDDEDIDDI
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分子量
19 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
EIF1AY, or Eukaryotic Translation Initiation Factor 1A Y-Linked, is a critical protein that plays a pivotal role in the initiation of protein synthesis by facilitating the binding of the ribosome to the mRNA. Research into EIF1AY has gained prominence due to its unique location on the Y chromosome and its potential implications in spermatogenesis and male fertility. Studies have indicated that EIF1AY is highly expressed in testicular tissues, suggesting its essential role in the development of spermatozoa. Additionally, recent investigations have linked mutations or dysregulation of EIF1AY with various male reproductive disorders, including infertility. As a result, recombinant EIF1AY protein has become a focal point for understanding its functional mechanisms and therapeutic potential. Researchers are employing recombinant DNA technology to produce EIF1AY protein for detailed biochemical studies, enabling exploration of its interactions with other translation initiation factors and its impact on cellular stress response and translation fidelity. The insights gleaned from these studies may not only enhance our grasp of male reproductive biology but also contribute to the development of innovative strategies for diagnosing and treating male infertility and related conditions.
