Analytical Data
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Gene name
ETNK2
- Application
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Alternative Names
ETNK2；EKI2;Ethanolamine kinase 2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9NVF9
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Expression Region
1-386aa
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AA Sequence
MGSSHHHHHHSSGLVPRGSHMGSMAVPPSAPQPRASFHLRRHTPCPQCSW GMEEKAAASASCREPPGPPRAAAVAYFGISVDPDDILPGALRLIQELRPH WKPEQVRTKRFTDGITNKLVACYVEEDMQDCVLVRVYGERTELLVDRENE VRNFQLLRAHSCAPKLYCTFQNGLCYEYMQGVALEPEHIREPRLFRLIAL EMAKIHTIHANGSLPKPILWHKMHNYFTLVKNEINPSLSADVPKVEVLER ELAWLKEHLSQLESPVVFCHNDLLCKNIIYDSIKGHVRFIDYEYAGYNYQ AFDIGNHFNEFAGVNEVDYCLYPARETQLQWLHYYLQAQKGMAVTPREVQ RLYVQVNKFALASHFFWALWALIQNQYSTIDFDFLRYAVIRFNQYFKVKP QASALEMPK
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Molecular Weight
47 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ETNK2 (Ectonucleotide Triphosphate Diphosphohydrolase 2) is a crucial enzyme involved in purinergic signaling and nucleotide metabolism, playing a significant role in cellular processes such as proliferation, differentiation, and apoptosis. As a member of the ecto-nucleotide triphosphate diphosphohydrolase family, ETNK2 is responsible for the hydrolysis of extracellular nucleotides, which can impact various physiological and pathological conditions, including inflammation, cancer, and neurodegenerative diseases. Recent studies have highlighted the relevance of ETNK2 in modulating purinergic signaling pathways, suggesting that altered ETNK2 activity may contribute to disease progression. The recombinant expression of ETNK2 in suitable systems has become essential for elucidating its biochemical functions and potential therapeutic applications. By producing ETNK2 in a controlled environment, researchers can study its enzymatic properties, interaction with substrates, and regulatory mechanisms. Characterizing this enzyme at the molecular level not only enhances the understanding of its role in cellular metabolism but also paves the way for developing targeted therapies that can manipulate its activity. The investigation of ETNK2 as a potential biomarker for specific diseases presents new avenues for early diagnosis and intervention, underscoring the importance of recombinant protein studies in advancing biomedical research.
