Analytical Data
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基因名
GPR89B
- Application
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别名
GPR89B; GPHRB; GPR89C; HSPC201; Golgi pH regulator B; Protein GPR89B
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P0CG08
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表达区间
1-455aa
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氨基酸序列
MSFLIDSSIMITSQILFFGFGWLFFMRQLFKDYEIRQYVVQVIFSVTFAFSCTMFELIIFEILGVLNSSSRYFHWKMNLCVILLILVFMVPFYIGYFIVSNIRLLHKQRLLFSCLLWLTFMYFFWKLGDPFPILSPKHGILSIEQLISRVGVIGVTLMALLSGFGAVNCPYTYMSYFLRNVTDTDILALERRLLQTMDMIISKKKRMAMARRTMFQKGEVHNKPSGFWGMIKSVTTSASGSENLTLIQQEVDALEELSRQLFLETADLYATKERIEYSKTFKGKYFNFLGYFFSIYCVWKIFMATINIVFDRVGKTDPVTRGIEITVNYLGIQFDVKFWSQHISFILVGIIIVTSIRGLLITLTKFFYAISSSKSSNVIVLLLAQIMGMYFVSSVLLIRMSMPLEYRTIITEVLGELQFNFYHRWFDVIFLVSALSSILFLYLAHKQAPEKQMAP
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分子量
52.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GPR89B, a member of the G protein-coupled receptor (GPCR) family, has recently garnered attention for its potential roles in cellular signaling and physiological regulation. GPCRs are integral membrane proteins that play crucial roles in transmitting extracellular signals into the cell, influencing a wide range of biological processes including metabolism, immune response, and neurobiology. Although GPR89B's specific functions have not been fully elucidated, preliminary studies suggest that it may be involved in the regulation of intracellular calcium levels and other critical signaling pathways. The interest in GPR89B has been fueled by its expression in various tissues and its potential implications in diseases such as cancer and metabolic disorders. Researchers are developing recombinant forms of GPR89B to investigate its structural characteristics, ligand interactions, and downstream signaling mechanisms. These studies are expected to provide insights into the physiological roles of GPR89B and its potential as a therapeutic target. Understanding the molecular dynamics and the functional mechanisms of GPR89B could lead to innovative strategies for drug development, particularly in the realm of targeted therapies that modulate GPCR activity. Overall, GPR89B represents a promising area of research within the expansive GPCR field, with the potential to unveil novel biological insights and therapeutic opportunities.
