Analytical Data
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基因名
FIBP
- Application
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别名
FIBP;Acidic fibroblast growth factor intracellular-binding Protein
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O43427
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表达区间
1-364aa
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氨基酸序列
MGSSHHHHHHSSGLVPRGSHMGSMTSELDIFVGNTTLIDEDVYRLWLDGY SVTDAVALRVRSGILEQTGATAAVLQSDTMDHYRTFHMLERLLHAPPKLL HQLIFQIPPSRQALLIERYYAFDEAFVREVLGKKLSKGTKKDLDDISTKT GITLKSCRRQFDNFKRVFKVVEEMRGSLVDNIQQHFLLSDRLARDYAAIV FFANNRFETGKKKLQYLSFGDFAFCAELMIQNWTLGAVGEAPTDPDSQMD DMDMDLDKEFLQDLKELKVLVADKDLLDLHKSLVCTALRGKLGVFSEMEA NFKNLSRGLVNVAAKLTHNKDVRDLFVDLVEKFVEPCRSDHWPLSDVRFF LNQYSASVHSLDGFRHQALWDRYMGTLRGCLLRLYHD
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分子量
44 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Fibroblast-specific protein 1 (FSP1), also known as FIBP or fibroblast activation protein, has gained significant attention in recent years due to its essential role in various physiological and pathological processes. This protein is primarily expressed in fibroblasts, playing critical roles in tissue remodeling, wound healing, and tumor microenvironment dynamics. The study of FIBP has become increasingly relevant in cancer research because it is associated with tumor progression and metastasis. Elevated levels of FIBP in the tumor stroma are linked to poor prognosis in several cancer types, implicating its involvement in promoting an aggressive tumor phenotype. Researchers aim to better understand the molecular mechanisms governing FIBP expression and its interactions with other cellular components. In addition, the development of recombinant FIBP proteins has opened new avenues for studying its functional properties and potential therapeutic applications. By leveraging advanced biotechnological methods, scientists are investigating ways to inhibit FIBP activity, which could lead to novel strategies for cancer treatment. This burgeoning field of research emphasizes the need for comprehensive studies that dissect FIBP's role in the tumor microenvironment and its potential as a biomarker for cancer prognosis, thus paving the way for innovative therapeutic interventions.
