Analytical Data
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Gene name
MT1E
- Application
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Alternative Names
MT1E；Metallothionein-1E
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P04732
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Expression Region
4-59aa
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AA Sequence
NCSCATGGSCTCAGSCKCKECKCTSCKKSCCSCCPVGCAKCAQGCVCKGASEKCSC
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Molecular Weight
32.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MT1E, a member of the metallothionein family, is a low-molecular-weight, cysteine-rich protein involved in metal ion homeostasis and detoxification. Research on MT1E has gained traction due to its significant role in cellular protection against heavy metal toxicity and oxidative stress. Studies have shown that MT1E can bind various heavy metals, such as cadmium and zinc, facilitating their removal or storage in cells, which is crucial for maintaining cellular metal balance. Additionally, the expression of MT1E has been linked to various physiological and pathological conditions, including cancer, neurodegenerative diseases, and inflammation. Its dysregulation can lead to increased sensitivity to oxidative damage and metal-induced toxicity, highlighting the importance of understanding its biological function and regulation. Recent advances in recombinant technology have enabled the production of MT1E in various host systems, facilitating detailed functional and structural studies. These insights open new avenues for therapeutic applications, particularly in developing strategies for metal detoxification and enhancing stress resistance in both plant and animal models. The ongoing investigation into the diverse roles of MT1E continues to reveal its potential as a biomarker for environmental exposure to heavy metals and its promising prospects in biomedical research.
