Analytical Data
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Gene name
FLRT3
- Application
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Alternative Names
FLRT3；KIAA1469;Leucine-rich repeat transmembrane Protein FLRT3
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9NZU0
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Expression Region
29-528aa
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AA Sequence
KSCPSVCRCD AGFIYCNDRF LTSIPTGIPE DATTLYLQNN QINNAGIPSD LKNLLKVERI YLYHNSLDEF PTNLPKYVKE LHLQENNIRT ITYDSLSKIP YLEELHLDDN SVSAVSIEEG AFRDSNYLRL LFLSRNHLST IPWGLPRTIE ELRLDDNRIS TISSPSLQGL TSLKRLVLDG NLLNNHGLGD KVFFNLVNLT ELSLVRNSLT AAPVNLPGTN LRKLYLQDNH INRVPPNAFS YLRQLYRLDM SNNNLSNLPQ GIFDDLDNIT QLILRNNPWY CGCKMKWVRD WLQSLPVKVN VRGLMCQAPE KVRGMAIKDL NAELFDCKDS GIVSTIQITT AIPNTVYPAQ GQWPAPVTKQ PDIKNPKLTK DHQTTGSPSR KTITITVKSV TSDTIHISWK LALPMTALRL SWLKLGHSPA FGSITETIVT GERSEYLVTA LEPDSPYKVC MVPMETSNLY LFDETPVCIE TETAPLRMYN PTTTLNREQE KEPYKNPNLP LEHHHHHH
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Molecular Weight
58 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
FLRT3 (Fibronectin Leucine-Rich Transmembrane Protein 3) is a member of the FLRT family and plays a crucial role in cell adhesion, migration, and signaling processes during development and tissue homeostasis. Its involvement in various biological pathways, particularly in neural development, has garnered attention due to its implications in neurodevelopmental disorders and cancer. FLRT3 functions by interacting with specific receptors and ligands, facilitating cell-to-cell interactions and influencing cytoskeletal dynamics. Previous studies have demonstrated that FLRT3 is vital for proper neural crest cell migration and vestibular system development, linking it to critical physiological processes. Furthermore, evidence suggests that aberrant expression of FLRT3 may correlate with cancer progression, making it a potential biomarker and therapeutic target. The recombinant production of FLRT3 protein enables the investigation of its structural and functional characteristics, paving the way for understanding its mechanistic roles in health and disease. By elucidating how FLRT3 contributes to cellular behaviors and signaling pathways, researchers aim to develop novel strategies for intervention in related pathologies and improve therapeutic outcomes. Overall, the study of FLRT3 recombinant protein represents a key area of interest that bridges developmental biology and clinical research, highlighting the significance of this protein in both fundamental and applied science.
