Analytical Data
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基因名
MYO7B
- Application
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别名
MYO7B；Unconventional myosin-VIIb
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6PIF6
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表达区间
全长
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氨基酸序列
full
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MYO7B (Myosin VIIB) is a member of the myosin superfamily of motor proteins, playing a crucial role in cellular processes, particularly in the transport and organization of cellular components. It is predominantly expressed in the inner ear and the retina, where it is essential for hair cell function and photoreceptor integrity. Mutations in the MYO7B gene have been linked to various auditory and visual disorders, including non-syndromic hearing loss and inherited retinal diseases. The study of MYO7B recombinant protein is vital for understanding its structure-function relationship, as well as its mechanisms of action. Investigating the protein’s interactions and pathways could reveal insights into the molecular underpinnings of associated diseases. Furthermore, MYO7B's potential as a therapeutic target or biomarker emphasizes the importance of recombinant protein research, facilitating the development of gene therapies or interventions aimed at correcting the functional deficits caused by MYO7B mutations. By producing and characterizing MYO7B recombinant protein, researchers can elucidate the protein's role in cellular dynamics, paving the way for novel strategies in treating related auditory and visual impairments.
