Analytical Data
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基因名
FXYD5
- Application
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别名
FXYD5；DYSAD；IWU1;FXYD domain-containing ion transport regulator 5
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q96DB9
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表达区间
1-178aa
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氨基酸序列
MSPSGRLCLLTIVGLILPTRGQTLKDTTSSSSADSTIMDIQVPTRAPDAVYTELQPTSPTPTWPADETPQPQTQTQQLEGTDGPLVTDPETHKSTKAAHPTDDTTTLSERPSPSTDVQTDPQTLKPSGFHEDDPFFYDEHTLRKRGLLVAAVLFITGIIILTSGKCRQLSRLCRNRCR
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分子量
19 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, 5% Trehalose
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Identification
Protein Description
FXYD5, part of the FXYD family of proteins, is a membrane protein that modulates sodium and potassium ion transport across cell membranes, significantly influencing cellular ion homeostasis. Its expression is predominantly found in cardiac tissues, where it plays a crucial role in regulating cardiac ion channels and, consequently, cardiac function. Dysregulation or altered expression of FXYD5 has been implicated in various cardiovascular diseases, including heart failure and arrhythmias. The study of FXYD5 has gained attention due to its potential role in cellular signaling pathways and its interaction with other membrane proteins, highlighting its importance in maintaining the physiological functioning of cardiomyocytes. For researchers, understanding the molecular mechanisms governing FXYD5 expression and function could pave the way for developing targeted therapeutic strategies aimed at treating cardiac conditions. Additionally, recombinant FXYD5 proteins offer a platform for exploring its biochemical properties, structure-function relationships, and interaction dynamics with other key proteins, thus enriching our understanding of cardiac physiology and pathophysiology.
