Analytical Data
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基因名
HBS1L
- Application
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别名
EF 1a; ERF3 similar protein; ERFS; HBS1; HBS1 like; HBS1 like protein; HBS1. S. cerevisiae. homolog of; HBS1-like (S. cerevisiae); HBS1-like protein; Hbs1l; HBS1L_HUMAN; Hsp70 subfamily B suppressor 1 like protein; HSPC276; KIAA1038
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y450
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表达区间
1-684aa
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氨基酸序列
MARHRNVRGYNYDEDFEDDDLYGQSVEDDYCISPSTAAQFIYSRRDKPSVEPVEEYDYEDLKESSNSVSNHQLSGFDQARLYSCLDHMREVLGDAVPDEILIEAVLKNKFDVQKALSGVLEQDRVQSLKDKNEATVSTGKIAKGKPVDSQTSRSESEIVPKVAKMTVSGKKQTMGFEVPGVSSEENGHSFHTPQKGPPIEDAIASSDVLETASKSANPPHTIQASEEQSSTPAPVKKSGKLRQQIDVKAELEKRQGGKQLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKAGKASFAYAWVLDETGEERERGVTMDVGMTKFETTTKVITLMDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQVNWQQERFQEITGKLGHFLKQAGFKESDVGFIPTSGLSGENLITRSQSSELTKWYKGLCLLEQIDSFKPPQRSIDKPFRLCVSDVFKDQGSGFCITGKIEAGYIQTGDRLLAMPPNETCTVKGITLHDEPVDWAAAGDHVSLTLVGMDIIKINVGCIFCGPKVPIKACTRFRARILIFNIEIPITKGFPVLLHYQTVSEPAVIKRLISVLNKSTGEVTKKKPKFLTKGQNALVELQTQRPIALELYKDFKELGRFMLRYGGSTIAAGVVTEIKE
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分子量
101.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HBS1L (HBS1 like, translational release factor) is a protein involved in the regulation of translation termination and ribosome recycling. It has garnered significant attention in recent years due to its potential implications in various biological processes, including hematopoiesis and immune responses. Research indicates that HBS1L plays a crucial role in maintaining normal erythropoiesis and has been implicated in disorders such as beta-thalassemia and sickle cell disease, where altered erythrocyte production and function occur. The development of recombinant HBS1L protein has been pursued to better understand its structural and functional properties, as well as its interactions with ribosomal components and other factors involved in protein synthesis. This recombinant protein serves as a valuable tool for elucidating mechanisms of translation regulation and investigating the protein's involvement in disease contexts. By studying HBS1L, researchers aim to uncover therapeutic targets and biomarkers that could lead to novel interventions for related hematological disorders, emphasizing its significance in both basic research and clinical applications.
