Analytical Data
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基因名
IFN-gamma R2
- Application
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别名
IFNGT1; AF-1; Interferon Gamma Transducer 1; Interferon gamma receptor accessory factor 1
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种属
Human
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表达系统
HEK293
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P38484
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表达区间
Met1~Gln247
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蛋白长度
Partial
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分子量
40kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
IFN-gamma R2, a receptor for interferon-gamma (IFN-γ), plays a crucial role in mediating immune responses, particularly in the context of viral infections and autoimmune diseases. As a key component of the Type II interferon signaling pathway, IFN-gamma R2 is involved in the activation of various immune cells, including macrophages and T cells, leading to enhanced expression of major histocompatibility complex (MHC) molecules and pro-inflammatory cytokines. Research has shown that dysregulation of IFN-gamma signaling can contribute to the pathogenesis of conditions such as chronic inflammatory diseases and cancer. Consequently, the study of recombinant IFN-gamma R2 protein has gained attention for its potential therapeutic applications. By producing this protein in a laboratory setting, researchers aim to explore its functional characteristics, improve understanding of its signaling mechanisms, and investigate its role in modulating immune responses. Moreover, recombinant IFN-gamma R2 could be utilized to develop targeted therapies for diseases where IFN-γ signaling is compromised or to enhance the effectiveness of existing treatments. Overall, understanding the biological properties and mechanisms of action of IFN-gamma R2 is essential for harnessing its potential in clinical applications, making it a focal point of immunological research.
