Analytical Data
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基因名
HNRPAB
- Application
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别名
ABBP 1; ABBP-1; ABBP1; Apobec 1 binding protein 1; APOBEC1 binding protein 1; APOBEC1-binding protein 1; Apolipoprotein B mRNA editing enzyme catalytic polypeptide 1- protein 1; FLJ40338; Heterogeneous nuclear ribonucleoprotein A/B; hnRNP A/B; hnRNP type A/B protein; HNRNPAB; HNRPAB; ROAA_HUMAN
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q99729
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表达区间
1-332aa
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氨基酸序列
MSEAGEEQPM ETTGATENGH EAVPEASRGR GWTGAAAGAG GATAAPPSGN QNGAEGDQIN ASKNEEDAGK MFVGGLSWDT SKKDLKDYFT KFGEVVDCTI KMDPNTGRSR GFGFILFKDA ASVEKVLDQK EHRLDGRVID PKKAMAMKKD PVKKIFVGGL NPESPTEEKI REYFGEFGEI EAIELPMDPK LNKRRGFVFI TFKEEEPVKK VLEKKFHTVS GSKCEIKVAQ PKEVYQQQQY GSGGRGNRNR GNRGSGGGGG GGGQSQSWNQ GYGNYWNQGY GYQQGYGPGY GGYDYSPYGY YGYGPGYDYS QGSTNYGKSQ RRGGHQNNYK PY
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分子量
36.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HNRPAB, or heterogeneous nuclear ribonucleoprotein A/B, is a multifunctional protein that plays a critical role in RNA metabolism, including splicing, transport, and stability of mRNA. As a part of the hnRNP family, HNRPAB interacts with pre-mRNA and various RNA species, influencing gene expression and cellular responses. Its aberrant expression has been linked to various diseases, particularly cancers, where it can contribute to the dysregulation of gene expression patterns and promote tumorigenesis. Research into recombinant HNRPAB protein aims to elucidate its specific functions, interactions, and regulatory mechanisms within the cell. By studying this protein in a controlled environment, scientists can uncover the molecular details of how HNRPAB influences RNA processing and stability. Furthermore, recombinant HNRPAB provides a platform for developing potential therapeutic interventions targeting its pathways. Understanding the roles and mechanisms of HNRPAB at a molecular level not only advances fundamental knowledge in RNA biology but also holds promise for finding strategies to combat diseases associated with its dysfunction. As such, the study of recombinant HNRPAB is vital for both basic research and potential clinical applications.
