Analytical Data
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Gene name
ANG3
- Application
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Alternative Names
ANG3；ANG3；ANG4；Angiopoietin-4
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O95841
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Expression Region
24-491aa
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AA Sequence
GQFKIKK INQRRYPRAT DGKEEAKKCA YTFLVPEQRI TGPICVNTKG QDASTIKDMI TRMDLENLKD VLSRQKREID VLQLVVDVDG NIVNEVKLLR KESRNMNSRV TQLYMQLLHE IIRKRDNSLE LSQLENKILN VTTEMLKMAT RYRELEVKYA SLTDLVNNQS VMITLLEEQC LRIFSRQDTH VSPPLVQVVP QHIPNSQQYT PGLLGGNEIQ RDPGYPRDLM PPPDLATSPT KSPFKIPPVT FINEGPFKDC QQAKEAGHSV SGIYMIKPEN SNGPMQLWCE NSLDPGGWTV IQKRTDGSVN FFRNWENYKK GFGNIDGEYW LGLENIYMLS NQDNYKLLIE LEDWSDKKVY AEYSSFRLEP ESEFYRLRLG TYQGNAGDSM MWHNGKQFTT LDRDKDMYAG NCAHFHKGGW WYNACAHSNL NGVWYRGGHY RSKHQDGIFW AEYRGGSYSL RAVQMMIKPI D
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ANG3, or angiogenin 3, is a member of the angiogenin family of proteins, which are crucial in various biological processes, including angiogenesis, neuroprotection, and cellular survival. While the most well-studied member, angiogenin (ANG), has established roles in promoting blood vessel formation and has implications in cancer and other diseases, ANG3 has garnered interest due to its potential unique functions and regulatory mechanisms in vascular biology. Research into ANG3 recombinant protein has been driven by the need to understand its structure-function relationships, interactions with RNA, and effects on gene expression, especially in the context of pathological conditions such as ischemia and neurodegenerative diseases. Initial studies suggest that ANG3 may play a role in modulating immune responses and inflammation, further expanding the scope of its biological significance. Investigating ANG3 through recombinant protein techniques offers insights into its therapeutic potential, paving the way for novel strategies in disease intervention, particularly for conditions where angiogenesis is disrupted. The generation of ANG3 recombinant protein facilitates detailed biochemical characterization and functional assays, enabling scientists to elucidate its precise mechanisms of action and role in disease progression. As such, ANG3 represents a promising target in the ongoing quest for effective therapies that harness the body’s natural angiogenic and protective responses.
