Analytical Data
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Gene name
HOXC13
- Application
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Alternative Names
ECTD9; Homeo box 3G; Homeo box C13; homeobox C13; Homeobox protein Hox 3G; Homeobox protein Hox-3G; Homeobox protein Hox-C13; Homeobox protein Hox-C13a; Hox-3G; HOX3; HOX3G ; Hoxc13; HXC13; HXC13_HUMAN; NUP98; NUP98/HOXC13
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P31276
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Expression Region
1-330aa
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AA Sequence
MTTSLLLHPRWPESLMYVYEDSAAESGIGGGGGGGGGGTGGAGGGCSGASPGKAPSMDGLGSSCPASHCRDLLPHPVLGRPPAPLGAPQGAVYTDIPAPEAARQCAPPPAPPTSSSATLGYGYPFGGSYYGCRLSHNVNLQQKPCAYHPGDKYPEPSGALPGDDLSSRAKEFAFYPSFASSYQAMPGYLDVSVVPGISGHPEPRHDALIPVEGYQHWALSNGWDSQVYCSKEQSQSAHLWKSPFPDVVPLQPEVSSYRRGRKKRVPYTKVQLKELEKEYAASKFITKEKRRRISATTNLSERQVTIWFQNRRVKEKKVVSKSKAPHLHST
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Molecular Weight
62.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HOXC13 is a member of the homeobox gene family, which plays a crucial role in the regulation of embryonic development and the differentiation of various cell types. Specifically, HOXC13 is implicated in the development of the hair and limb structures. Abnormal expression of HOXC13 has been associated with various developmental disorders and diseases, including congenital anomalies and some forms of cancer. Research into recombinant HOXC13 protein is important for understanding its functional mechanisms at the molecular level. By producing recombinant HOXC13 protein, scientists can investigate its role in gene regulation and protein interactions, which may provide insights into its involvement in developmental pathways. The study of HOXC13 also has therapeutic implications, as it may help identify strategies for correcting developmental defects or targeting cancerous cells that exhibit altered HOXC13 expression. Furthermore, analyzing the structure and function of recombinant HOXC13 protein can lead to a better understanding of the homeobox gene family's contributions to gene transcription and developmental biology, thereby advancing our knowledge in regenerative medicine and gene therapy. Overall, the research on HOXC13 recombinant protein is vital for elucidating the complexities of gene regulation in development and disease.
