Analytical Data
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Gene name
GSTO1
- Application
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Alternative Names
GSTO1;GSTTLP28;Glutathione S-transferase omega-1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P78417
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Expression Region
2-241aa
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AA Sequence
SGESARSLG KGSAPPGPVP EGSIRIYSMR FCPFAERTRL VLKAKGIRHE VININLKNKP EWFFKKNPFG LVPVLENSQG QLIYESAITC EYLDEAYPGK KLLPDDPYEK ACQKMILELF SKVPSLVGSF IRSQNKEDYA GLKEEFRKEF TKLEEVLTNK KTTFFGGNSI SMIDYLIWPW FERLEAMKLN ECVDHTPKLK LWMAAMKEDP TVSALLTSEK DWQGFLELYL QNSPEACDYG L
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GSTO1 (Glutathione S-transferase omega 1) is a member of the glutathione S-transferase enzyme family, which plays a crucial role in detoxification processes by catalyzing the conjugation of glutathione to various endogenous and exogenous compounds. The enzyme is involved in cellular defense against oxidative stress and has been implicated in various physiological and pathological conditions, including cancer and neurodegenerative diseases. Recent studies have highlighted the genomic polymorphisms of GSTO1, which may influence individual susceptibility to diseases and response to therapies. Furthermore, the protein exhibits unique substrate specificity compared to other GST isoforms, making it a potential target for drug development. The recombinant expression of GSTO1 in various systems has enabled researchers to investigate its structural and functional properties, providing insights into its enzymatic mechanisms and interactions with other cellular components. Understanding the role of GSTO1 in cellular processes and disease mechanisms could pave the way for novel therapeutic strategies, potentially enhancing the efficacy of existing treatments and reducing adverse effects associated with chemotherapy. The ongoing research into GSTO1’s properties, including its role in pharmacogenomics and drug metabolism, underscores its significance in biomedical research and therapeutic innovation.
