Analytical Data
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基因名
IFI44L
- Application
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别名
IFI44L; C1orf29; GS3686Interferon-induced protein 44-like
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q53G44
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表达区间
1-452aa
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氨基酸序列
MEVTTRLTWN DENHLRKLLG NVSLSLLYKS SVHGGSIEDM VERCSRQGCT ITMAYIDYNM IVAFMLGNYI NLHESSTEPN DSLWFSLQKK NDTTEIETLL LNTAPKIIDE QLVCRLSKTD IFIICRDNKI YLDKMITRNL KLRFYGHRQY LECEVFRVEG IKDNLDDIKR IIKAREHRNR LLADIRDYRP YADLVSEIRI LLVGPVGSGK SSFFNSVKSI FHGHVTGQAV VGSDITSITE RYRIYSVKDG KNGKSLPFML CDTMGLDGAE GAGLCMDDIP HILKGCMPDR YQFNSRKPIT PEHSTFITSP SLKDRIHCVA YVLDINSIDN LYSKMLAKVK QVHKEVLNCG IAYVALLTKV DDCSEVLQDN FLNMSRSMTS QSRVMNVHKM LGIPISNILM VGNYASDLEL DPMKDILILS ALRQMLRAAD DFLEDLPLEE TGAIERALQP CI
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分子量
51.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
IFI44L (Interferon-Inducible Protein 44 Like) is a member of the interferon-stimulated gene family and plays a pivotal role in the immune response, particularly in antiviral defense mechanisms. Its expression is highly regulated and induced by type I interferons, which are secreted in response to viral infections. Research has indicated that IFI44L may influence various cellular processes, including apoptosis, cell proliferation, and the modulation of immune signaling pathways. In recent years, studies have focused on its potential role in chronic viral infections, autoimmune diseases, and cancer, highlighting the protein's significance in both innate and adaptive immunity. Investigating the structure and function of recombinant IFI44L is crucial for understanding its biological activities and therapeutic potential. The recombinant protein has been used in various assays to elucidate its interactions with other cellular proteins, its effect on viral replication, and its influence on immune cell responses. Understanding the molecular mechanisms by which IFI44L exerts its effects could provide insights into developing novel therapeutic strategies for treating viral infections and immune-related disorders. This research area continues to evolve, revealing the multifaceted role of IFI44L in health and disease.
