Analytical Data
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Gene name
HLF
- Application
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Alternative Names
HLF;Hepatic leukemia factor
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q16534
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Expression Region
1-295aa
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AA Sequence
MEKMSRPLPL NPTFIPPPYG VLRSLLENPL KLPLHHEDAF SKDKDKEKKL DDESNSPTVP QSAFLGPTLW DKTLPYDGDT FQLEYMDLEE FLSENGIPPS PSQHDHSPHP PGLQPASSAA PSVMDLSSRA SAPLHPGIPS PNCMQSPIRP GQLLPANRNT PSPIDPDTIQ VPVGYEPDPA DLALSSIPGQ EMFDPRKRKF SEEELKPQPM IKKARKVFIP DDLKDDKYWA RRRKNNMAAK RSRDARRLKE NQIAIRASFL EKENSALRQE VADLRKELGK CKNILAKYEA RHGPL
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
HLF (Hepatic Leukemia Factor) is a transcription factor that plays a crucial role in various biological processes, including cell differentiation, proliferation, and metabolism. Recent studies have highlighted its significance in liver function, hematopoiesis, and stem cell regulation. The interest in HLF recombinant proteins has grown due to their potential applications in therapeutic contexts, particularly in regenerative medicine and cancer treatment. Research has shown that HLF can influence the expression of genes involved in liver regeneration and hematopoietic stem cell maintenance, making it a promising target for developing novel treatments for liver diseases and hematological disorders. Furthermore, understanding the molecular mechanisms through which HLF operates can provide insights into its role in oncogenesis and tumor progression. As a result, scientists are increasingly focused on producing HLF recombinant proteins to explore their functional properties and potential therapeutic implications. These efforts encompass both the optimization of expression systems and the characterization of the proteins to facilitate studies that could lead to clinical applications. The advances in biotechnology and protein engineering also enable researchers to modify HLF for enhanced stability and activity, paving the way for innovative strategies in drug design and gene therapy. Overall, the exploration of HLF recombinant proteins represents a frontier in biomedical research, merging molecular biology with therapeutic strategies to address unmet clinical needs.
