Analytical Data
-
基因名
IGHA2
- Application
-
别名
IGHA2Immunoglobulin heavy constant alpha 2; Ig alpha-2 chain C region; Ig alpha-2 chain C region BUT; Ig alpha-2 chain C region LAN
-
种属
Human
-
表达系统
E. coli
-
标签
GST-tag at N-terminal
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
P01877
-
表达区间
1-477aa
-
氨基酸序列
MKHLWFFLLLVAAPRWVLSQVQLQESGPGLVKPSETLSLTCTVSGGSISSYYWSWIRQTAGKGLEWIGYISHSGSTTYNPSLKSRVTLSLDTSKNQFSLRLNSVTAADTAVYYCAHGSSWDFAFDYWGQGTLVTVSSASPTSPKVFPLSLDSTPQDGNVVVACLVQGFFPQEPLSVTWSESGQNVTARNFPPSQDASGDLYTTSSQLTLPATQCPDGKSVTCHVKHYTNPSQDVTVPCPVPPPPPCCHPRLSLHRPALEDLLLGSEANLTCTLTGLRDASGATFTWTPSSGKSAVQGPPERDLCGCYSVSSVLPGCAQPWNHGETFTCTAAHPELKTPLTANITKSGNTFRPEVHLLPPPSEELALNELVTLTCLARGFSPKDVLVRWLQGSQELPREKYLTWASRQEPSQGTTTFAVTSILRVAAEDWKKGDTFSCMVGHEALPLAFTQKTIDRLAGKPTHVNVSVVMAEVDGTCY
-
分子量
78 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
IGHA2, a member of the immunoglobulin superfamily, encodes the immunoglobulin A (IgA) chain, playing a critical role in the immune response, particularly in mucosal immunity. IgA, a dimeric form found predominantly in mucosal secretions, such as saliva, tears, and gastrointestinal secretions, acts as a first line of defense against pathogens. Understanding the structure and function of IGHA2 and its encoded protein is essential for insights into immunological processes and the development of various diseases, including autoimmune disorders and infections. Recent advancements in recombinant protein technology have facilitated the production of IGHA2, allowing for detailed studies of its properties and interactions. Research into IGHA2 recombinant proteins aims to elucidate their biological functions, roles in immune regulation, and potential therapeutic applications. Furthermore, understanding variations in IGHA2 expression and secretion is vital, as anomalies can lead to deficiencies in mucosal immunity or contribute to pathological conditions. Overall, IGHA2 recombinant protein research holds promise for improving vaccine design, developing immunotherapies, and enhancing our understanding of immune system dynamics.
