Analytical Data
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基因名
HNRNPC
- Application
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别名
HNRNPC;HNRPC;Heterogeneous nuclear ribonucleoProteins C1/C2
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种属
Human
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表达系统
E. coli
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标签
N-6His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P07910
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表达区间
1-293aa
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氨基酸序列
MGSSHHHHHHSSGLVPRGSHMASNVTNKTDPRSMNSRVFIGNLNTLVVKK SDVEAIFSKYGKIVGCSVHKGFAFVQYVNERNARAAVAGEDGRMIAGQVL DINLAAEPKVNRGKAGVKRSAAEMYGSSFDLDYDFQRDYYDRMYSYPARV PPPPPIARAVVPSKRQRVSGNTSRRGKSGFNSKSGQRGSSKSGKLKGDDL QAIKKELTQIKQKVDSLLENLEKIEKEQSKQAVEMKNDKSEEEQSSSSVK KDETNVKMESEGGADDSAEEGDLLDDDDNEDRGDDQLELIKDDEKEAEEG EDDRDSANGEDDS
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分子量
45 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Identification
Protein Description
The HNRNPC protein, or heterogeneous nuclear ribonucleoprotein C, is a crucial component of the spliceosomal machinery involved in pre-mRNA processing. It plays a significant role in the regulation of gene expression, influencing alternative splicing and mRNA stability. Research into HNRNPC has gained momentum due to its involvement in various cellular processes and implications in human diseases, particularly cancers and neurodegenerative disorders. Its function in organizing RNA metabolism and modulating interactions between RNA and proteins makes it a key player in the post-transcriptional regulation of gene expression. Additionally, emerging studies suggest that alterations in HNRNPC expression and function may contribute to disease pathogenesis, highlighting the need for a deeper understanding of its biological roles. The recombinant expression and characterization of HNRNPC provide significant insights into its structure and function, enabling researchers to investigate its mechanisms and potential as a therapeutic target. Overall, HNRNPC represents a pivotal focus in molecular biology and biomedical research, revealing important connections between RNA processing and disease.
