Analytical Data
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基因名
Cxcl11
- Application
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别名
Cxcl11；ITAC；SCYB11；SCYB9B；C-X-C motif chemokine 11
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O14625
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表达区间
22-94aa
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氨基酸序列
FPMFKRGRCLCIGPGVKAVKVADIEKASIMYPSNNCDKIEVIITLKENKG QRCLNPKSKQARLIIKKVERKNF
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分子量
8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CXCL11, also known as I-TAC (interferon-inducible T cell alpha chemoattractant), is a chemokine belonging to the CXC family that plays a crucial role in immune responses and inflammatory processes. It primarily attracts T cells, particularly Th1 cells, and has been implicated in various pathological conditions, including autoimmune diseases, cancer, and viral infections. Research on recombinant CXCL11 protein has gained significance due to its potential applications in therapeutic strategies, including enhancing anti-tumor immunity and modulating chronic inflammatory responses. Recombinant protein production allows for the study of its biological activities, interactions with receptors, and signaling pathways, which are essential for understanding its function in the immune system. Additionally, the development of CXCL11 as a therapeutic agent could provide novel approaches for immunotherapy, especially in malignancies where T cell recruitment is limited. Understanding the structure-function relationship of CXCL11 through recombinant technology can further elucidate its roles in health and disease, offering insights that could lead to innovative treatment modalities.
