Analytical Data
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基因名
ITGB1BP2
- Application
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别名
ITGB1BP2; MSTP015; Integrin beta-1-binding protein 2; Melusin
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UKP3
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表达区间
1-347aa
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氨基酸序列
MSLLCRNKGCGQHFDPNTNLPDSCCHHPGVPIFHDALKGWSCCRKRTVDFSEFLNIKGCTMGPHCAEKLPEAPQPEGPATSSSLQEQKPLNVIPKSAETLRRERPKSELPLKLLPLNISQALEMALEQKELDQEPGAGLDSLIRTGSSCQNPGCDAVYQGPESDATPCTYHPGAPRFHEGMKSWSCCGIQTLDFGAFLAQPGCRVGRHDWGKQLPASCRHDWHQTDSLVVVTVYGQIPLPAFNWVKASQTELHVHIVFDGNRVFQAQMKLWGVINVEQSSVFLMPSRVEISLVKADPGSWAQLEHPDALAKKARAGVVLEMDEEESDDSDDDLSWTEEEEEEEAMGE
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分子量
64.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ITGB1BP2, or Integrin beta-1 binding protein 2, is a crucial regulator in various cellular processes, including cell adhesion, migration, and proliferation. Its interaction with integrins, particularly the beta-1 subunit, implicates it in critical pathways associated with tissue development and repair. Research has demonstrated that ITGB1BP2 plays a significant role in cancer biology, notably influencing tumor progression and metastasis. This has sparked interest in elucidating its structure and function, particularly through the study of recombinant proteins. By expressing and purifying ITGB1BP2 as a recombinant protein, researchers aim to better understand its biological mechanisms and potential as a therapeutic target. Furthermore, studying its interactions with integrins and other binding partners can provide insights into its role in pathological conditions, including fibrosis and inflammatory diseases. Ultimately, characterizing ITGB1BP2 in a recombinant form facilitates the development of targeted interventions and contributes to the broader understanding of integrin-mediated signaling pathways.
