Cat: PA1000-1668

Recombinant Human Il1a Protein,His

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Analytical Data

  • 基因名

    Il1a

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    IL1A;IL1F1;Interleukin-1 alpha

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    P01583

  • 表达区间

    113-271aa

  • 氨基酸序列

    SAPFSFLSNVKYNFMRIIKYEFILNDALNQSIIRANDQYLTAAALHNLDEAVKFDMGAYKSSKDDAKITVILRISKTQLYVTAQDEDQPVLLKEMPEIPKTITGSETNLLFFWETHGTKNYFTSVAHPNLFIATKQDYWVCLAGGPPSITDFQILENQA

  • 分子量

    20.0 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

Interleukin-1 alpha (IL-1α) is a key cytokine in the immune response, playing a crucial role in the regulation of inflammation and the activation of immune cells. It is primarily produced by activated macrophages and epithelial cells, and is involved in a wide array of biological processes, including cellular proliferation, differentiation, and apoptosis. The dysregulation of IL-1α is linked to various inflammatory diseases, autoimmune disorders, and even cancer, making it a significant target for therapeutic interventions. Research on recombinant IL-1α has gained momentum due to its potential applications in understanding these diseases and developing novel treatments. By producing recombinant IL-1α, scientists aim to explore its functional properties, investigate its signaling pathways, and evaluate its effects on various cell types in vitro and in vivo. Furthermore, recombinant IL-1α can be utilized in drug development, vaccine formulation, and therapeutic strategies for managing diseases associated with aberrant IL-1 signaling. The growing interest in targeted therapies has fueled studies on its structure-function relationship and the development of IL-1α inhibitors, indicating its promise in improving clinical outcomes for patients suffering from IL-1-related pathologies. Overall, the research on recombinant IL-1α continues to advance our understanding of its crucial role in immune modulation and highlights its relevance in developing effective therapeutic strategies for diverse diseases.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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