Analytical Data
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Gene name
KIAA1394
- Application
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Alternative Names
CARNS1; ATPGD1; KIAA1394; Carnosine synthase 1; EC 6.3.2.11; ATP-grasp domain-containing protein 1
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
A5YM72
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Expression Region
1-385aa
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AA Sequence
MTEHRRDEENARLLAELVRARGLKLDGCFSYWDDCLVLTALLCQELGLPCSSPAALRLAKQKSLTQLHLLHHHGPPWPAPSLHAVPCCPLESEADVERAVHQVPLPGVMKLEFGAGAVGVRLVEDAPQCHEHFSRITRDLQGEADHPGIGLGWGNAMLLMEFVEGTEHDVDLVLFGGRLLAAFVSDNGPTRLPGFTETAACMPTGLAPEQEAQMVQAAFRCCLGCGLLDGVFNVELKLTGAGPRLIEINPRMGGFYLRDWILELYGVDLLLAAVMVACGLRPALPTRPRARGHLVGVMCLVSQHLQALSSTASRETLQALHDRGLLRLNLLEEALVPGEYEEPYCSVACAGPSPTEARLRLLGLCQGLGIDGPSYPVAHFLSHFK
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Molecular Weight
68.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
KIAA1394, also known as KIAA1394 protein or FAM190A, is a protein encoded by the KIAA1394 gene, which has garnered attention in recent years due to its potential implications in various biological processes and diseases. Initially identified through large-scale sequencing projects, KIAA1394 is thought to play roles in cellular functions such as cell cycle regulation, DNA damage response, and apoptosis. Its expression patterns have been found to be altered in several types of cancers, suggesting that it may serve as a prognostic biomarker or therapeutic target in oncology. Additionally, studies have indicated that KIAA1394 may be involved in neurodevelopmental disorders, further underscoring its importance in human health. Despite its relevance, the precise molecular mechanisms underlying KIAA1394 function remain largely elusive, necessitating further investigation into its structure, interactions, and biological roles. Researchers are employing techniques such as gene editing, proteomics, and cellular assays to elucidate the functions of KIAA1394, aiming to unravel its contributions to disease mechanisms and identify potential interventions to modulate its activity. This ongoing research reflects a growing interest in understanding the complex roles of KIAA1394 in both normal physiology and pathological conditions, paving the way for future studies that may translate into novel therapeutic strategies.
