Analytical Data
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Gene name
KIAA1967
- Application
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Alternative Names
CCAR2; DBC1; KIAA1967Cell cycle and apoptosis regulator protein 2; Cell division cycle and apoptosis regulator protein 2; DBIRD complex subunit KIAA1967; Deleted in breast cancer gene 1 protein; DBC-1; DBC.1; NET35; p30 DBC
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8N163
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Expression Region
5-365aa
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AA Sequence
LPEKVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEPKDEAQNEGPATESEAPLKEDGLLPKPLSSGGEEEEKPRGEASEDLCEMALDPELLLLRDDGEEEFAGAKLEDSEVRSVASNQSEMEFSSLQDMPKELDPSAVLPLDCLLAFVFFDANWCGYLHRRDLERILLTLGIRLSAEQAKQLVSRVVTQNICQYRSLQYSRQEGLDGGLPEEVLFGNLDLLPPPGKSTKPGAAPTEHKALVSHNGSLINVGSLLQRAEQQDSGRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLAEAEETARTAERQKSQLQRLLQELRRRLTPLQLEIQRVVEKADSWVEKEEPAPSN
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Molecular Weight
65.45 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KIAA1967 is a gene that encodes a protein implicated in various cellular processes, including cell proliferation, differentiation, and genomic stability. Its expression has been linked to several physiological and pathological conditions, making it a subject of interest in biomedical research. Recent studies suggest that KIAA1967 may play a role in cancer biology, particularly in tumorigenesis and metastasis, due to its involvement in regulating key signaling pathways. Moreover, KIAA1967 has been identified as a potential biomarker for certain cancers, providing insight into its utility in early diagnosis and treatment strategies. Given its multifaceted roles, researchers are increasingly focused on characterizing the structure and function of the KIAA1967 recombinant protein. This research aims to deepen our understanding of the molecular mechanisms underlying its actions and its interactions with other proteins. By employing techniques such as protein expression, purification, and functional assays, scientists aim to elucidate the biological significance of KIAA1967. Advancements in this field could pave the way for innovative therapeutic approaches targeting KIAA1967 in cancer and other diseases, highlighting the importance of this protein in health and disease.
