Analytical Data
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基因名
LSM5
- Application
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别名
LSM5;U6 snRNA-associated Sm-like Protein LSm5
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y4Y9
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表达区间
1-91aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSMAANATT NPSQLLPLEL VDKCIGSRIH IVMKSDKEIV GTLLGFDDFV NMVLEDVTEF EITPEGRRIT KLDQILLNGN NITMLVPGGE GPEV
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分子量
12 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
LSM5 is a protein complex that plays a critical role in mRNA processing and regulation in eukaryotic cells. It is comprised of several subunits, including LSM proteins, which are essential for mRNA stabilization, decapping, and degradation processes. The research background of LSM5 is rooted in understanding its function in the context of RNA metabolism, particularly how it interacts with other RNA-binding proteins and cellular pathways. Studies have shown that LSM5 is involved in the life cycle of mRNA, from transcription to translation, and its dysregulation can lead to various cellular dysfunctions and diseases, including cancer. Furthermore, LSM5 has been implicated in responses to environmental stresses, highlighting its importance in cellular adaptation and survival. Research on LSM5 focuses on elucidating its molecular mechanisms, determining its role in mRNA turnover, and exploring its potential as a therapeutic target. Understanding LSM5 is crucial for comprehending the complexities of gene expression regulation and its implications in human health and disease.
