Analytical Data
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Gene name
KLF7
- Application
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Alternative Names
KLF7; KLF7_HUMAN; Krueppel like factor 7; Krueppel-like factor 7; Kruppel like factor 7; Ubiquitous krueppel like factor ; Ubiquitous krueppel-like factor; UKLF
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O75840
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Expression Region
1-302aa
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AA Sequence
MDVLASYSIF QELQLVHDTG YFSALPSLEE TWQQTCLELE RYLQTEPRRI SETFGEDLDC FLHASPPPCI EESFRRLDPL LLPVEAAICE KSSAVDILLS RDKLLSETCL SLQPASSSLD SYTAVNQAQL NAVTSLTPPS SPELSRHLVK TSQTLSAVDG TVTLKLVAKK AALSSVKVGG VATAAAAVTA AGAVKSGQSD SDQGGLGAEA CPENKKRVHR CQFNGCRKVY TKSSHLKAHQ RTHTGEKPYK CSWEGCEWRF ARSDELTRHY RKHTGAKPFK CNHCDRCFSR SDHLALHMKR HI
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Molecular Weight
33.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
KLF7, or Krüppel-like factor 7, is a member of the Krüppel-like factor family of transcription factors, playing significant roles in various biological processes such as cell differentiation, proliferation, and metabolism. The dysregulation of KLF7 has been implicated in several diseases, including diabetes, cardiovascular disorders, and cancer, making it a critical target for research. Recent studies have shown that KLF7 is involved in regulating insulin signaling and β-cell function, highlighting its potential in diabetes therapy. Additionally, KLF7's role in adipogenesis and muscle differentiation suggests its importance in metabolic regulation and body composition. The expression and activity of KLF7 can be influenced by various signaling pathways, including those mediated by growth factors and hormones, which underscores the complexity of its regulatory mechanisms. Research into recombinant KLF7 protein focuses on its structure-function relationship and biological activities, facilitating the understanding of its mechanisms and interactions at the molecular level. By studying KLF7 in a recombinant system, scientists aim to unravel its therapeutic potential, elucidate its role in metabolic diseases, and explore its applicability as a biomarker or target for interventions. The production of recombinant KLF7 not only provides a tool for further functional studies but also enhances the potential for designing novel therapeutic strategies that can modulate its activity in disease contexts. Through the comprehensive exploration of KLF7's biological significance and therapeutic relevance, this field holds promise for advancing our understanding of metabolic diseases and developing innovative treatments.
