Analytical Data
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Gene name
MSRB2
- Application
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Alternative Names
MSRB2;CBS-1;MSRB;Methionine-R-sulfoxide reductase B2. mitochondrial
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9Y3D2
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Expression Region
21-182aa
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AA Sequence
VRGQAGGGGP GTGPGLGEAG SLATCELPLA KSEWQKKLTP EQFYVTREKG TEPPFSGIYL NNKEAGMYHC VCCDSPLFSS EKKYCSGTGW PSFSEAHGTS GSDESHTGIL RRLDTSLGSA RTEVVCKQCE AHLGHVFPDG PGPNGQRFCI NSVALKFKPR KH
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The research on MSRB2 (Methionine Sulfoxide Reductase B2) recombinant proteins has gained significant attention due to its crucial role in cellular stress response and redox regulation. MSRB2 is an enzyme that repairs oxidatively damaged proteins by reducing methionine sulfoxide back to methionine, thereby protecting cells from oxidative stress, which is implicated in various diseases, including neurodegenerative disorders and cancer. Understanding the structure and function of MSRB2 is essential for elucidating its biological mechanisms and potential therapeutic applications. Recent advances in recombinant protein technology have allowed for the production of MSRB2 in model systems, enabling detailed biochemical assays, structural studies, and functional analyses. These studies aim to explore the enzyme's kinetic properties, substrate specificity, and interaction with other cellular pathways, which can lead to insights into the development of novel antioxidant therapies. By investigating the molecular characteristics of MSRB2, researchers hope to advance our knowledge of oxidative stress response and uncover new strategies for mitigating its detrimental effects on health.
