Analytical Data
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Gene name
LENG1
- Application
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Alternative Names
LENG1; Leukocyte receptor cluster member 1
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96BZ8
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Expression Region
1-264aa
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AA Sequence
MNILPKKSWHVRNKDNVARVRRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVDLFRELLEEGKGVIRGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQRPKEPPSLDQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRRRRYNSQFNPQLARRPRQQDPHLTH
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Molecular Weight
56.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
LENG1 (Leukocyte Receptor Cluster 1) is a member of the LENG family of proteins, which are believed to play significant roles in immune regulation and cellular signaling. Research on LENG1 has intensified due to its potential involvement in various cellular processes, including apoptosis, cell proliferation, and immune response modulation. Understanding LENG1 enhances our knowledge of the immune system, particularly how immune cells communicate and respond to environmental stressors. Notably, studies have indicated that LENG1 expression levels correlate with certain diseases, including autoimmune disorders and cancers. The protein's unique structural features, including its multiple leucine-rich repeat motifs, suggest it may function as a receptor or play a role in cell-cell interactions. Investigations into the biochemical properties of LENG1 and its functional implications are crucial for the development of targeted therapies and diagnostics. As researchers continue to explore the molecular mechanisms underlying LENG1's action, the findings could lead to novel strategies for modulating immune responses, providing insights into treatment options for conditions where the immune system is either overactive or underactive.
