Analytical Data
-
基因名
MYOZ1
- Application
-
别名
MYOZ1;MYOZ;Myozenin-1
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q9NP98
-
表达区间
1-299aa
-
氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSMPLSGTP APNKKRKSSK LIMELTGGGQ ESSGLNLGKK ISVPRDVMLE ELSLLTNRGS KMFKLRQMRV EKFIYENHPD VFSDSSMDHF QKFLPTVGGQ LGTAGQGFSY SKSNGRGGSQ AGGSGSAGQY GSDQQHHLGS GSGAGGTGGP AGQAGRGGAA GTAGVGETGS GDQAGGEGKH ITVFKTYISP WERAMGVDPQ QKMELGIDLL AYGAKAELPK YKSFNRTAMP YGGYEKASKR MTFQMPKFDL GPLLSEPLVL YNQNLSNRPS FNRTPIPWLS SGEPVDYNVD IGIPLDGETE EL
-
分子量
34 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The MYOZ1 protein, also known as myozap, is a member of the myozenin family and plays a significant role in cardiac and skeletal muscle development and function. Research into MYOZ1 has gained traction due to its involvement in muscle contraction regulation and its potential implications in various myopathies and cardiovascular diseases. This protein is localized in the Z-disc of striated muscle cells, where it interacts with other structural proteins, helping to maintain sarcomere integrity. The study of MYOZ1 has highlighted its important role in connecting signaling pathways to the contractile apparatus, thereby influencing muscle performance. Additionally, emerging evidence suggests that alterations in MYOZ1 expression or function may contribute to the pathogenesis of conditions such as hypertrophic cardiomyopathy and dilated cardiomyopathy. Understanding the molecular mechanisms underlying MYOZ1's functions could pave the way for developing therapeutic strategies aimed at mitigating muscle-related disorders. As research progresses, MYOZ1 is increasingly recognized not only for its structural significance but also for its potential as a biomarker and therapeutic target in muscle diseases. Consequently, elucidating the role of MYOZ1 in muscle pathology is crucial for advancing both basic and clinical research in muscle physiology and related disorders.
