Analytical Data
-
基因名
LXRb
- Application
-
别名
LXRb；LXRB；NER；UNR；Oxysterols receptor LXR-beta
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
P55055
-
表达区间
1-460aa
-
氨基酸序列
MSSPTTSSLD TPLPGNGPPQ PGAPSSSPTV KEEGPEPWPG GPDPDVPGTD EASSACSTDW VIPDPEEEPE RKRKKGPAPK MLGHELCRVC GDKASGFHYN VLSCEGCKGF FRRSVVRGGA RRYACRGGGT CQMDAFMRRK CQQCRLRKCK EAGMREQCVL SEEQIRKKKI RKQQQESQSQ SQSPVGPQGS SSSASGPGAS PGGSEAGSQG SGEGEGVQLT AAQELMIQQL VAAQLQCNKR SFSDQPKVTP WPLGADPQSR DARQQRFAHF TELAIISVQE IVDFAKQVPG FLQLGREDQI ALLKASTIEI MLLETARRYN HETECITFLK DFTYSKDDFH RAGLQVEFIN PIFEFSRAMR RLGLDDAEYA LLIAINIFSA DRPNVQEPGR VEALQQPYVE ALLSYTRIKR PQDQLRFPRM LMKLVSLRTL SSVHSEQVFA LRLQDKKLPP LLSEIWDVHE
-
分子量
50.9 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Liver X receptors (LXRs), specifically LXRα and LXRβ, are nuclear receptors that play crucial roles in regulating lipid metabolism, cholesterol homeostasis, and inflammatory responses. The understanding of LXRβ, in particular, has gained significant attention due to its involvement in various physiological and pathological processes, including metabolic disorders and cardiovascular diseases. LXRβ is activated by oxysterols, which are metabolites derived from cholesterol, and upon activation, it regulates the expression of target genes involved in lipid synthesis and transport. Given its central role in maintaining cellular lipid balance, LXRβ has emerged as a potential therapeutic target for treating conditions like atherosclerosis and non-alcoholic fatty liver disease. Research into LXRβ recombinant proteins enables scientists to explore its functional mechanisms in detail and assess how it interacts with ligands and other cellular pathways. By studying LXRβ at a molecular level, researchers can elucidate its regulatory roles and potential as a drug target, providing insights for the development of novel therapies aimed at metabolic diseases. Overall, the investigation of LXRβ recombinant proteins represents a promising avenue for advancing our understanding of lipid metabolism and developing clinically relevant interventions.
