Analytical Data
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基因名
PFDN1
- Application
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别名
PFDN1;PFD1;Prefoldin subunit 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O60925
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表达区间
14-122aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MTELQAKVID TQQKVKLADI QIEQLNRTKK HAHLTDTEIM TLVDETNMYE GVGRMFILQS KEAIHSQLLE KQKIAEEKIK ELEQKKSYLE RSVKEAEDNI REMLMARRAQ
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分子量
15 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PFDN1, or P30, is a protein that plays a crucial role in the assembly and stabilization of protein complexes within cells, particularly in the context of the chaperonin complex. Research into PFDN1 has garnered attention due to its involvement in various cellular processes, including protein folding, transport, and regulation of cellular stress responses. Given its essential functions, abnormalities in PFDN1 expression or function have been linked to several diseases, particularly neurodegenerative disorders and cancer. The study of recombinant PFDN1 protein allows researchers to explore its structural and functional properties in detail, facilitating the understanding of its role in health and disease. By producing this protein through recombinant technology, scientists can investigate its interactions with other proteins, its influence on protein folding dynamics, and its potential as a therapeutic target. Furthermore, insights gained from PFDN1 studies could lead to the development of new strategies for drug design and disease management, highlighting its importance in both fundamental biology and clinical applications.
