Analytical Data
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Gene name
ABCA2
- Application
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Alternative Names
ABCA2；ABC2；KIAA1062；ATP-binding cassette sub-family A member 2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9BZC7
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Expression Region
全长
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AA Sequence
full
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Molecular Weight
269.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ABCA2 (ATP-binding cassette sub-family A member 2) is a member of the ATP-binding cassette (ABC) transporter family, which plays a crucial role in the transport of various molecules across cellular membranes. Research into ABCA2 has gained prominence due to its involvement in several physiological processes and pathological conditions, including lipid metabolism, neurological function, and the immune response. Notably, ABCA2 is expressed in the brain and has been linked to neurodegenerative diseases, suggesting its potential role in cellular homeostasis and the clearance of toxic metabolites. Studies have shown that ABCA2 may influence cholesterol transport and modulate the risk for conditions such as Alzheimer's disease. Moreover, the protein has been identified in immune cells, indicating a broader role in immune system functionality. To further elucidate the mechanisms by which ABCA2 operates and its contributions to health and disease, researchers are increasingly focusing on the expression, function, and regulation of this protein. Recombinant ABCA2 protein, produced using modern biotechnological methods, serves as a valuable tool for studying its structural and biochemical properties. Understanding how ABCA2 interacts with various substrates and its functional implications could lead to novel therapeutic approaches in managing diseases associated with ABCA2 dysfunction. Overall, the study of ABCA2 recombined protein represents a promising frontier in both molecular biology and potential clinical applications, aiming to unlock solutions for complex health issues stemming from its dysregulation.
