Analytical Data
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基因名
Gi24
- Application
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别名
VSIR;C10orf54;SISP1;VISTA;V-type immunoglobulin domain-containing suppressor of T-cell activation
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9H7M9
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表达区间
33-194aa
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氨基酸序列
FKVATPYSLYVCPEGQNVTLTCRLLGPVDKGHDVTFYKTWYRSSRGEVQT CSERRPIRNLTFQDLHLHHGGHQAANTSHDLAQRHGLESASDHHGNFSIT MRNLTLLDSGLYCCLVVEIRHHHSEHRVHGAMELQVQTGKDAPSNCVVYP SSSQDSENITAA
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分子量
45 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The Gi24 recombinant protein, derived from the human Gi protein family, has drawn significant attention in the field of molecular biology and biochemistry due to its critical role in various signaling pathways. Gi proteins, known for their involvement in mediating inhibitory signaling for G-protein coupled receptors (GPCRs), play a pivotal role in numerous physiological processes, including neurotransmission, immune responses, and cellular growth regulation. Gi24, as a specific isoform, has been implicated in modulating pathways that affect cell fate and proliferation, making it a potential target for therapeutic interventions in diseases such as cancer and neurodegenerative disorders. Research on the Gi24 recombinant protein focuses on understanding its structure-function relationships, interaction with other cellular components, and its overall influence on signaling networks. By deciphering these mechanisms, scientists aim to leverage Gi24's properties to develop novel strategies for drug discovery and disease treatment, highlighting its significance as a biomarker and therapeutic target in modern medicine.
