Cat: PA2000-9486

Recombinant Human MRPS30 Protein,His

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Analytical Data

  • Gene name

    MRPS30

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    28S ribosomal protein S30; 28S ribosomal protein S30; mitochondrial; Mitochondrial 28S ribosomal protein S30; mitochondrial; Mitochondrial ribosomal protein S30; MRP S30; MRP-S30; MRPS30; PAP; PDCD9; Programmed cell death 9; Programmed cell death protein 9; RT30_HUMAN; S30mt

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9NP92

  • Expression Region

    1-439 aa

  • AA Sequence

    MAAARCWRPL LRGPRLSLHT AANAAATATE TTCQDVAATP VARYPPIVAS MTADSKAARL RRIERWQATV HAAESVDEKL RILTKMQFMK YMVYPQTFAL NADRWYQYFT KTVFLSGLPP PPAEPEPEPE PEPEPALDLA ALRAVACDCL LQEHFYLRRR RRVHRYEESE VISLPFLDQL VSTLVGLLSP HNPALAAAAL DYRCPVHFYW VRGEEIIPRG HRRGRIDDLR YQIDDKPNNQ IRISKQLAEF VPLDYSVPIE IPTIKCKPDK LPLFKRQYEN HIFVGSKTAD PCCYGHTQFH LLPDKLRRER LLRQNCADQI EVVFRANAIA SLFAWTGAQA MYQGFWSEAD VTRPFVSQAV ITDGKYFSFF CYQLNTLALT TQADQNNPRK NICWGTQSKP LYETIEDNDV KGFNDDVLLQ IVHFLLNRPK EEKSQLLEN

  • Molecular Weight

    50.3 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

MRPS30, or Mitochondrial Ribosomal Protein S30, is a key component of the mitochondrial ribosome, playing a critical role in protein synthesis within the mitochondria, which are vital organelles responsible for energy production in eukaryotic cells. Recent studies have highlighted the importance of MRPS30 in various cellular processes, including mitochondrial biogenesis, metabolism, and apoptosis. Abnormalities in mitochondrial function are associated with a range of diseases, including neurodegenerative disorders, metabolic syndrome, and cancer. Consequently, understanding the structure and function of MRPS30, as well as its interactions with other mitochondrial proteins, is essential for elucidating the mechanisms underlying mitochondrial dysfunction. Research into MRPS30 may also provide insights into potential therapeutic targets for mitochondrial-related diseases. The investigation of MRPS30, particularly through the study of its recombinant protein forms, can unlock important information about its biological functions and its role in maintaining mitochondrial integrity and functionality. By employing various techniques such as crystallography, molecular dynamics simulations, and functional assays, researchers aim to characterize MRPS30's structure and its contributions to ribosomal assembly and translation processes. Overall, the study of MRPS30 and its recombinant forms is a promising area of research with significant implications for understanding mitochondrial biology and addressing related health challenges.

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