Analytical Data
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基因名
PTGDS
- Application
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别名
PTGDS;PDS;Prostaglandin-H2 D-isomerase
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P41222
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表达区间
23-190aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MAPEAQVSVQ PNFQQDKFLG RWFSAGLASN SSWLREKKAA LSMCKSVVAP ATDGGLNLTS TFLRKNQCET RTMLLQPAGS LGSYSYRSPH WGSTYSVSVV ETDYDQYALL YSQGSKGPGE DFRMATLYSR TQTPRAELKE KFTAFCKAQG FTEDTIVFLP QTDKCMTEQ
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分子量
21 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PTGDS (Prostaglandin D2 Synthase) is a protein associated with various physiological and pathological processes, including inflammation, neurodegeneration, and cancer. This enzyme catalyzes the conversion of prostaglandin H2 to prostaglandin D2, a potent bioactive lipid that plays a critical role in regulating sleep, immune responses, and differentiation of certain cell types. Research has increasingly focused on PTGDS due to its involvement in modulating inflammatory pathways and its potential as a therapeutic target in diseases such as asthma and neurological disorders. Furthermore, the understanding of PTGDS's structure and function opens avenues for designing specific inhibitors or modulators that can regulate its activity. The recombinant production of PTGDS facilitates detailed studies of its biochemical properties and interactions, enabling researchers to explore its role in various biological contexts and to develop new therapeutic strategies. Given its significance in both basic and translational research, PTGDS continues to be a key focus in the fields of biochemistry and pharmacology.
