Analytical Data
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基因名
INSM1
- Application
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别名
INSM1；IA1；Insulinoma-associated Protein 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q01101
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表达区间
1-510aa
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氨基酸序列
MPRGFLVKRSKKSTPVSYRVRGGEDGDRALLLSPSCGGARAEPPAPSPVPGPLPPPPPAERAHAALAAALACAPGPQPPPQGPRAAHFGNPEAAHPAPLYSPTRPVSREHEKHKYFERSFNLGSPVSAESFPTPAALLGGGGGGGASGAGGGGTCGGDPLLFAPAELKMGTAFSAGAEAARGPGPGPPLPPAAALRPPGKRPPPPTAAEPPAKAVKAPGAKKPKAIRKLHFEDEVTTSPVLGLKIKEGPVEAPRGRAGGAARPLGEFICQLCKEEYADPFALAQHKCSRIVRVEYRCPECAKVFSCPANLASHRRWHKPRPAPAAARAPEPEAAARAEAREAPGGGSDRDTPSPGGVSESGSEDGLYECHHCAKKFRRQAYLRKHLLAHHQALQAKGAPLAPPAEDLLALYPGPDEKAPQEAAGDGEGAGVLGLSASAECHLCPVCGESFASKGAQERHLRLLHAAQVFPCKYCPATFYSSPGLTRHINKCHPSENRQVILLQVPVRPAC
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分子量
52.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
INSM1 (Insulinoma-Associated Protein 1) is a transcription factor that plays a significant role in the development of neuroendocrine tumors, particularly neuroblastoma and insulinoma. Its expression is often associated with the differentiation of neuroendocrine cells, making it a crucial marker for studying these tumors. Research on INSM1 has gained momentum due to its potential implications in cancer diagnostics and therapeutics. The protein functions by regulating various downstream target genes involved in cell proliferation and differentiation. Understanding the molecular mechanisms and pathways involving INSM1 could provide insights into tumorigenesis and the behavior of neuroendocrine tumors. Additionally, recombinant INSM1 protein is being investigated for its potential use in various experimental models to better understand its biological functions and therapeutic applications. The study of INSM1 not only enhances our knowledge of neuroendocrine tumors but also opens avenues for novel treatment strategies, targeting the pathways where INSM1 plays a pivotal role. Thus, research on INSM1 recombinant protein is essential for advancing our understanding of neuroendocrine tumor biology and improving clinical outcomes for patients affected by such malignancies.
